This session provides a detailed overview of SUD and involves reviews of information and strategies to assist those in need of help with this challenge. The session covers the spectrum of use, neurobiological responses to substances, theories that explain the disorders, public health impact and epidemiology, comorbidity, and treatment options. The objective of this session is to provide participants with a deeper understanding of this disorder and how we can help family, friends, co-workers, and others who are struggling.